5 Essential Elements For phenobarbital sodium route of administration
Monitor Carefully (1)pentobarbital will lessen the level or effect of fentanyl intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead on to the lessen in fentanyl plasma concentrations, lack of efficacy or, possibly, enhancement of the wit